Abstract
been reported on its long term use. Cranberry (Vaccinium macrocarpon) is rich in polyphenols, including flavonoids and proanthrocyanidins. Insufficient
evidences are available to support antimicrobial property of Cranberry extract mouthwash in context to red, orange and green complexes of periodontal
pathogens and even comparison of same with clinically used and accepted 0.2% Chlorhexidine.
MATERIALS AND METHODS: Sterilised nutrient agar plates were inoculated with suspensions of P. gingivalis, T. forsythia, P. intermedia and A.
actinomycetemcomitans (overnight cultures grown at 37° on nutrient agar). The strains were allowed to grow in strict anaerobic condition. 1, 5, 10 and 15 mg/
ml Cranberry extract, 0.2% Chlorhexidine and distilled water were added into wells. Plates were then again incubated at 37° for 24 hours. Diameter of zones
of inhibition of all the plates was measured using digital vernier callipers. The mean score of zones of inhibition was calculated.
RESULTS: Results of the study showed that all four concentrations of Cranberry extract showed comparatively less significant antimicrobial property against
the microorganisms, compared to 0.2% Chlorhexidine.
CONCLUSION: This study showed that 1, 5, 10 and 15
Keywords
References
Lamont RJ, Jenkinson HF. Subgingival colonization by Porphyromonas gingivalis. Oral Microbiol
Immunol 2000; 15:341–9.
Teles RP, Teles FR. Antimicrobial agents used in the control of periodontal biofilms: Effective adjuncts to mechanical plaque control. Braz Oral Res 2009;23(1):39–48.
Mandel ID. Chemotherapeutic agents for controlling plaque and gingivitis. J Clin Periodontol 1988;15: 488–98.
Ribeiro LG, Hashizume LN, Maltz M. The effect of different formulations of chlorhexidine in reducing level of mutans streptococci in the oral cavity. J Dent 2007;35: 359–70.
Addy M, Moran M, Newcomb R, Warren P. The comparative tea staining potential of phenolic,
Chlorhexidine and antiadhesive mouth-rinses. J Clin Periodontol 1995;22:929–34.
Cowan MM. Plant products as antimicrobial agents. Clin Microbiol Rev 1999;12:564–82.
Vvedenskaya IO, Rosen RT, Guido JE, Russell DJ, Mills KA, Vorsa N. Characterization of flavonols in cranberry (Vaccinium macrocarpon) powder. J Agric Food Chem 2004;52:188–95.
Cimolai N, Cimolai T. The cranberry and the urinary tract. Eur J Clin Microbiol Infect Dis 2007;26:767–76.
Chatelain K, Phippen S, McCabe J, Teeters CA, O’Malley S, Kingsley K. Cranberry and grape
seed extracts inhibit the proliferative phenotype of oral squamous cell carcinomas. Evid Based Complement Alternat Med 2011;2011:1–12.
Prasain JK, Jones K, Moore R, Barnes S, Leahy M, Roderick R, et al. Effect of cranberry juice concentrate
on chemically- induced urinary bladder cancers. Oncol Rep 2008;19:1565–70.
Bonifait L, Grenier D. Cranberry polyphenols: potential benefits for dental caries and periodontal
disease. J Can Dent Assoc 2010;76:a130.
Sethi R, Govila V. Inhibitory effect of cranberry juice on the colonization of Streptococci species:
an in-vitro study. J Indian Soc Periodontol 2011;15(1):46–50.
Polak D, Naddaf R, Shapira L, Weiss EI et al. Protective potential of non-dialyzable material fraction of cranberry juice on the virulence of P. gingivalis and F. nucleatum mixed infection. J Periodontol 2013;84:1019–25.
Khairnar MR, Karibasappa GN, Dodamani AS, Vishwakarma P et al. Comparative assessment
of Cranberry and Chlorhexidine mouthwash on streptococcal colonization among dental students:
a randomized parallel clinical trial.Contemp Clin Dent 2015;6(1):35–9.
Gupta A, Bansal K, Marwaha M. Effect of highmolecular- weight component of Cranberry on
plaque and salivary Streptococcus mutans counts in children: an in vivo study. J Indian Soc Pedod Prev Dent 2015;33:128–33.
Gregoire S, Singh AP, Vorsa N, Koo H. Influence of cranberry phenolics on glucan synthesis by
glucosyltransferases and Streptococcus mutans acidogenicity. J Appl Microbiol 2007;103:1960–8.
Refbacks
- There are currently no refbacks.