Journal of Periodontal Practice

Login
Notifications
Font Size

Management of Drug Induced Gingival Enlargement: A Case Report

Anup Patil, Apurva Pisal, Siddhartha A. Varma, Girish Suragimath, Keshava Abbayya, Sameer Zope, Vishwajeet Kale

Abstract


This article reviews the etiology, pathogenesis and AED associated with gingival overgrowth, in addition to its multidisciplinary management and prevention.
Although the pharmacologic effect of each of these drugs is different and directed toward various primary target tissues, all of them seem to act similarly on a
secondary target tissue, i.e., the gingival connective tissue, causing common clinical and histopathological findings.

Keywords


Gingival, Mandibular, Epithelium, Drug

Full Text:

References


American Academy of Periodontology. Informational paper: drug associated gingival enlargement. J

Periodontol 2004;75:1424–31.

Desai P, Silver JG. Drug-induced gingival enlargements. J Can Dent Assoc 1998;64:263–8.

Brunet L, Miranda J, Farré M, Berini L, Mendieta C. Gingival enlargement induced by drugs. Drug Saf

;15:219–31.

Coletta RD, Graner E. Hereditary gingival fibromatosis: a systematic review. J Periodontol

;77:753–64.

Angelopoulos AP, Goaz PW. Incidence of diphenyl hydantoin gingival hyperplasia. Oral Surg Oral Med Oral

Pathol 1972;34:898–906.

Glickman I, Lewitus M. Hyperplasia of the gingiva associated with dilantin (sodium

diphenyl hydantoinate) therapy. J Am Dent Assoc 1941;28:1991.

Dongari-Bagtzoglou A, Research, Science and Therapy Committee, American Academy

of Periodontology. Drug-associated gingival enlargement. J Periodontol 2004;75:1424–31.

Doufexi A, Mina M, Ioannidou E. Gingival overgrowth in children: Epidemiology, pathogenesis, and

complications. A literature review. J Periodontol 2005;76:3–10.

Hallmon WW, Rossmann JA. The role of drugs in the pathogenesis of gingival overgrowth. A

collective review of current concepts. Periodontol 2000 1999;21:176–96.

Dongari-Bagtzoglou A. Research, Science and Therapy Committee, American Academy of Periodontology. Drug-associated gingival enlargement. J Periodontol 2004;75:1424–31.


Refbacks

  • There are currently no refbacks.