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Carcinoma Ovary Masquerading as Metastatic Hepatocellular Carcinoma—Case Report

Amitabh Kumar Upadhyay, Chandragouda Dodagoudar, Pankaj Goyal, Rakesh Gupta, Nidhi Gupta, Vijay Jagad


Malignant tumors with hepatoid features resembling hepatocellular carcinoma have been described in different sites. These tumore are very rare and are found particularly in the stomach, ovary, pancreas, renal pelvis and urinary bladder. Hepatoid variant of carcinoma ovary was first of all reported by Isikura and Scully in 1987. Till date, with the best of our knowledge, only 21 patients with diagnosis of Hepatoid carcinoma of ovary have been reported. No case has been reported from India till date. This is a case of 56 years female presented to us with a complaint of abdominal distension, pain and weight loss of 2 months duration. Omental Biopsy was suggestive of hepatocellular carcinoma. On IHC, tumor cells were positive for HepPar 1, Glypican 3 and focal positivity for CK7 while negative for SALL4, PAX8, CK20 and TTF 1. She underwent interval cytoreductive surgery in January 2014. Final HPE report was hepatoid variant of carcinoma ovary.



Hepatoid carcinoma ovary

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