Journal of Pharmaceutical and Biomedical Sciences

Case Study on Systemic Lupus Erythematosus

Tamilselvi D

Abstract


Systemic lupus erythematosus (SLE) is a chronic, multisystem, autoimmune disease of the connective tissues and blood vessels characterized by inflammation in potentially any body tissue its course and symptoms are variable and unpredictable with mild to life threatening complications. The cause of SLE is not known. It appears to result from a complex interaction of genetics with an unidentified trigger that activates the disease. Suspected trigger include exposure to ultraviolet light, estrogen, pregnancy, infections and drugs. Genetic predisposition to SLE is evidenced in an increased concordance rate in twins (tenfold), increased incidence within family members (10% to 16%).

Keywords


SLE chronic, multisystem, autoimmune disease, inflammation

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