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Evaluation of Habit Patterns and Clinical Findings of Oral Submucous Fibrosis in South Indian Population

C. Sridhar, C. Anuradha, C. Krithika, Ramachandran Sudarshan

Abstract


Objective To evaluate the habit patterns and clinical features of oral submucous fibrosis.
Materials and Methods A hospital-based cross sectional study was conducted in a sample of 75 subjects with clinically diagnosed oral submucous fibrosis. Prior to the treatment, a detailed habit history was elicited. Clinical symptoms and signs were recorded. Mouth opening, cheek flexibility and tongue protrusion were also recorded.
Results 93.33% had the habit of using processed areca nut products like Gutkha (54.66%), Mawa (20%). The burning sensation was the most common symptom seen in 82% of cases, followed by restricted mouth opening. Blanching and palpable fibrous bands were present in all cases. The mean mouth opening of the sample was 32.73 (±9.10) mm, cheek flexibility was 6.48 (±3.06) mm, and tongue protrusion was 43.92 (±10.24) mm.
Conclusion It is important to be familiar with the habit patterns and clinical features of oral submucous fibrosis to facilitate early diagnosis and prompt management to reduce oral cancer-related morbidity and mortality

Keywords


oral submucosa fibrosis, oral cavity, areca nuts

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References


More CB, Gupta S, Joshi J, Varma SN. Classification system for oral submucous fibrosis. J Indian Acad Oral Med Radiol. 2012;24(1):24–29.

Warnakulasuriya S, Johnson N, Van der Waal I. Nomenclature and classification of potentially malignant disorders of the oral mucosa. J Oral Pathol Med. 2007;36(10):575–580.

Pillai R, Balaram P, Reddiar KS. Pathogenesis of oral submucous fibrosis. Relationship to risk factors associated with oral cancer.Cancer, 1992;69(8);2011–2020.

Sudarshan R, Annigeri RG, Vijayabala GS, Krithiika C. Oral sub-mucous fibrosis: realities of etiology. Arch Oral Res.2012;8(2);153–160.

Sinor PN, Gupta PC, Murti PR, Bhonsle RB, Daftary DK, Mehta FS, et al. A case-control study of oral submucous fibrosis with special reference to the etiologic role of areca nut. J Oral Pathol Med. 1990;19(2):94–98.

Rajalalitha P, Vali S. Molecular pathogenesis of oral submucous fibrosis – a collagen metabolic disorder. J Oral Pathol Med. 2005;34(6):321–328.

Fedorowicz Z, Chan Shih-Yen E, Dorri M, Nasser M, Newton T, Shi L. Interventions for the management of oral submucous fibrosis. Cochrane Database Syst Rev. 2008;4:CD007156. doi:10.1002/14651858.CD007156.pub2.

Tilakaratne WM, Klinikowski MF, Saku T, Peters TJ, Warnakulasuriya S. Oral submucous fibrosis: Review on aetiology and pathogenesis. Oral Oncol. 2006;42(6):561–568.

Aziz SR. Oral submucous fibrosis: case report and review of diagnosis and treatment. J Oral Maxillofacial Surg. 2008;66(11):2386–2389.

Kerr A, Warnakulasuriya S, Mighell A, Dietrich T, Nasser M, Rimal J, et al. A systematic review of medical interventions for oral submucous fibrosis and future research opportunities. Oral Dis.2011;17(s1):42–57.

Reddy V, Wanjari P, Banda NR, Reddy P. Oral submucous fibrosis: Correlation of clinical grading to various habit factors. Int J Dental Clin. 2011;3(1):21–24.

Gupta P, Sinor P, Bhonsle R, Pawar V, Mehta H. Oral submucous fibrosis in India: a new epidemic? Natl Med J India. 1998;11(3):113–116.

Kumar K, Saraswathi T, Ranganathan K, Devi U, Elizabeth J. Oral submucous fibrosis: A clinico-histopathological study in Chennai. Ind J Dental Res. 2007;18(3):106.

Gupta VK, Malhotra S, Patil R, Tripathi A. Oral submucous fibrosis at pediatric age, now time to think: Series of two cases. Ind J Med Paediat Oncol. 2013;34(2):107.

Gupta PC, Ray CS. Smokeless tobacco and health in India and South Asia. Respirology. 2003;8(4):419–431.

Gupta PC, Ray CS. Tobacco and youth in the South East Asian region. Ind J Cancer. 2002;39(1):5–34.

Ahmad MS, Ali S, Ali A, Chaubey K. Epidemiological and etiological study of oral submucous fibrosis among gutkha chewers of Patna, Bihar, India. J Ind Soc Pedodont Prevent Dentist.

;24(2):84.

Babu S, Venkataramana Bhat R, Uday Kumar P, Sesikaran B, Visweswara Rao K, Aruna P, et al. A comparative clinico-pathological study of oral submucous fibrosis in habitual chewers of pan masala and betelquid. Clin Toxicol. 1996;34(3):317–322.

Shah N, Sharma P. Role of chewing and smoking habits in the etiology of oral submucous fibrosis (OSF): a case?control study. J Oral Pathol Med. 1998;27(10):475–479.

Lee C, Ko Y, Huang H, Chao Y, Tsai C, Shieh T, et al. The precancer risk of betel quid chewing, tobacco use and alcohol consumption in oral leukoplakia and oral submucous fibrosis in southern Taiwan. British J Cancer. 2003;88(3):366–372.

Ariyawardana A, Athukorala A, Arulanandam A. Effect of betel chewing, tobacco smoking and alcohol consumption on oral submucous fibrosis: a case–control study in Sri Lanka. J Oral Pathol Med. 2006;35(4):197–201.

Krishnamoorthy B, Khan M. Management of oral submucous fibrosis by two different drug regimens: A comparative study. Dental Res J. 2013;10(4):527.

Kumar A, Bagewadi A, Keluskar V, Singh M. Efficacy of lycopene in the management of oral submucous fibrosis. Oral Surg Oral Med Oral Pathol Oral Radiol Endodontol. 2007;103(2):207–213.

Gupta S, Khanna S, Singh M, Singh P. Histological changes to palatal and paratubal muscles in oral submucous fibrosis. J Laryngol Otol. 2000;114(12):947–950.

Ali FM, Patil A, Patil K, Prasant M. Oral submucous fibrosis and its dermatological relation. Indian Dermatol Online J. 2014;5(3):260.

Joseph AP, Rajendran R. Submucosa precedes lamina propria in initiating fibrosis in oral submucous fibrosis-evidence based on collagen histochemistry. J Oral Maxillofacial Pathol. 2010;1(1):3–7.

Zain RB, Ikeda N, Gupta PC, Warnakulasuriya S, Wyk CW, Shrestha P, et al. Oral mucosal lesions associated with betel quid, areca nut and tobacco chewing habits: consensus from a workshop held in Kuala Lumpur, Malaysia, November 25?27, 1996. J Oral Pathol Med. 1999;28(1):1–4.

Pindborg J, Mehta F, Gupta P, Daftary D. Prevalence of oral submucous fibrosis among 50,915 Indian villagers. British journal of cancer. 1968;22(4):646.

Khanna J, Andrade N. Oral submucous fibrosis: a new concept in surgical management: report of 100 cases. Int J Oral Maxillofacial Surg. 1995;24(6):433–439.

Cox S, Walker, D. Oral submucous fibrosis. A review. Australian Dent J. 1996;41(5):294–299.Wahi P, Kapur V, Luthra UK, Srivastava M. Submucous fibrosis of the oral cavity. 1. Clinical features. Bulletin of the World Health Organization. 1996;35(5):789.

Zawawi KH, Al-Badawi EA, Lobo SL, Melis M, Mehta NR. An index for the measurement of normal maximum mouth opening.J Canadian Dental Association, 2003;69(11):737–741.


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