Abstract
Introduction Myolipoma of soft tissue is an extremely rare benign lipomatous lesion, which was originally described by Meis et al. (1991). Myolipomas affect adults most frequently in the 5th and 6th decades of life with a female predilection (2:1 ratio). The
lesions are most commonly located in the abdominal cavity, retroperitoneum and inguinal areas. Less frequently, myolipomas may be found at sites such as the orbit, eyelid, breast, pericardium, anus, neck and even the extremities. We herewith, report a case of subcutaneous myolipoma presenting at a rare site: nape of neck.
Case History A 26-year-old gentleman presented in surgical OPD complaining of swelling in nape of the neck since 2 months. His medical history did not reveal any co-morbid conditions, all routine investigations have been done that were within normal limits.
Material and Methods A surgical excision was performed and biopsy demonstrated a myolipoma. Gross examination showed a well-circumscribed mass measuring of 3 × 3 × 2 cm. The outer surface was smooth and the cut surface showed greyish white solid area. On microscopic examination, lobules of mature adipose tissue with intervening fibrous septae containing thin-walled vessels and thick bands of muscle fibres and the final diagnosis of myolipoma was performed.
Conclusion We report a rare case of subcutaneous myolipoma at the rare site in young male patient. Despite the benign nature of these tumors, the correct diagnosis is important, because such masses need to be considered in the differential diagnosis of fat-containing lesions of the soft tissue.
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References
Meis JM, Enzinger FM. Myolipoma of soft tissue. Am J Surg Pathol. 1991;15:121–125.
Liang EY, Cooper JE, Lam WW, Chung SC, Allen PW, Metreweli C. Case report: myolipoma or liposarcoma: a mistaken identity in the retroperitoneum. Clin Radiol. 1996;51:295–297.
Guillou L, Coindre JM. Newly described adipocytic lesions. Semin Diagn Pathol. 2001;18:238–249.
Nagayama A, Miyamura N, Lu Z. Light and electron microscopic findings in a patient with orbital myolipoma. Graefes Arch Clin Exp Ophthalmol. 2003;241:773–776.
Sharara N, Lee WR, Weir C. Myolipoma of the eyelid. Graefes Arch Clin Exp Ophthalmol. 1998;236:630–634.
McGregor DK, Whitman GJ, Middleton LP. Myolipoma of the breast: mammographic, sonographic, and pathologic correlation. Breast J. 2004;10:259–260.
Ben-Izhak O, Elmalach I, Kerner H, Best LA. Pericardial myolipoma: a tumour presenting as a mediastinal mass and containing oestrogen receptors. Histopathology. 1996;29:184–186.
Lee YS, Park SE, Lee JU, Choi ES. MRI of a subcutaneous myolipoma in the ankle: a case report. Korean J Radiol. 2011;12:641–645.
Christopher D, Unni K, Mertens F. Adipocytic tumors. In: Fletcher CD, Unni KK, Mertens F, (eds): Pathology and genetics: tumors of soft tissue and bone. Lyon: IARC; 2002. pp. 19–46. (World Health Organization classification of tumours; 4).
Murphey MD, Carroll JF, Flemming DJ, Pope TL, Gannon FH, Kransdorf MJ. From the archives of the AFIP: benign musculoskeletal lipomatous lesions. Radiographics. 2004;24:1433–66.
Weiss SW, Goldblum JR. Benign lipomatous tumors, 4th ed. In: Weiss SW, Goldblum JR, (eds): Enzinger and Weiss’s soft tissue tumors. St Louis: Mosby; 2001. pp. 571–639.
Michal M. Retroperitoneal myolipoma: a tumour mimicking retroperitoneal angiomyolipoma and liposarcoma with myosarcomatous differentiation. Histopathology. 1994;25(1):86–88.
Sonobe H, Ohtsuki Y, Iwata J, Furihata M, Ido E, Hamada I. Myolipoma of the round ligament: report of a case with a review of the English literature. Virchows Archiv. 1995;427(4):455–458.
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