Study of Correlation of Waist–Hip Ratio and Lipid Profile in Type-2 Diabetes Mellitus Subjects

Gulab Kanwar; Kshetrapal Singh Shekhawat; Shalini Rathore; Kusum Bala Jain

Study of Correlation of Waist–Hip Ratio and Lipid Profile in Type-2 Diabetes Mellitus Subjects

Gulab Kanwar, Kshetrapal Singh Shekhawat, Shalini Rathore, Kusum Bala Jain

Abstract

India is being called the diabetic capital of the world, with over 30 million diabetic individuals. Anthropometric parameters have evolved into reliable indicators for predicting the incidence of diabetes mellitus.

Materials and Methods A total of 100 patients collected from New Medical Hospital, Kota (Rajasthan), India. Weight, height, waist circumference (WC) and hip circumference were measured. Waist–hip ratio (WHR) was calculated. Samples were analysed on autoanalyser.

Results and Discussion In the present study, we found that the WHR is not significantly associated with lipid parameters in male patients except for TG and high-density lipoprotein (HDL). Non-significant correlation was obtained in female patients. Statistically negative significant correlation was found in serum for HDL between fifth and sixth decade of life. No significant correlation was found in any other age groups.

Summary and Conclusion WC and WHR are the important indicators of obesity and can be used to predict incidence of obesity in Indian population. Further broad study is advised.

Keywords

lipid profile, waist–hip ratio, diabetes mellitus

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References

Powers AC. Diabetes mellitus in: Harrison’s principles of internal medicine, 17th ed., In: Fauci AS, Braunwald E, Kasper DL, Hauser SL, Longo DL, Jameson JL, et al. (eds). New Delhi: McGraw Hill; 2008. p. 2275–3002.

Visscher TL, Kromhout D, Seidell JC. Long-term and recent time trends in the prevalence of obesity among Dutch men and women. Int J Obes Relat Metab Disord. 2002;26:1218–24.

Ho SC, Chen YM, Woo JL, Leung SS, Lam TH, Janus ED. Association between simple anthropometric indices and cardiovascular risk factors. Int J Obes Relat Metab Disord. 2001;25:1689–97.

Han TS, McNeill G, Seidell JC, Lean ME. Predicting intra-abdominal fatness from anthropometric measures: the influence of stature. Int J Obes Relat Metab Disord. 1997;21:587–93.

Lemieux S, Prud’homme D, Bouchard C, Tremblay A, Despres JP. A single threshold value of waist girth identifies normal-weight and overweight subjects with excess visceral adipose tissue. Am J Clin Nutr. 1996;64:685–93.

Hartz A, Rupley D, Rimm A. The association of girth measurements with disease in 32,856 women. Am J Epidemiol. 1984;119:71–80.

Ohlson LO, Larsson B, Svardsudd K, Welin L, Eriksson H, Wilhelmsen L, et al. The influence of body fat distribution on the incidence of diabetes mellitus: 13.5 years of follow-up of the participants in the study of men born in 1913. Diabetes. 1985;35:1055–8.

Berber A, Gómez-Santos R, Fanghänel G, Sánchez-Reyes L. Anthropometric indexes in the prediction of type 2 diabetes mellitus, hypertension and dyslipidemia in a Mexican population. Int J Obes Relat Metab Disord. 2001;25:1794–9.

Expert panel on detection, evaluation, and treatment of high blood cholesterol in adults. Executive summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (adult treatment panel III). JAMA. 2001;285:2486–97.

Despres JP, Allard C, Tremblay A, Talbot J, Bouchard C. Evidence for a regional component of body fatness in the association with serum lipids in men and women. Metabolism. 1985;34:967–973.

Denke MA, Sempos CT, Grundy SM. Excess body weight: an under-contributor to high blood cholesterol in White American men. Arch Int Med. 1993;153:1093–1103.

Hu D, Hannah J, Gray RS, Jablonski KA, Henderson JA, Robbins DC, et al. Effects of obesity and body fat distribution on lipids and lipoproteins in nondiabetic American Indians: the strong heart study. Obes Res. 2000;8:411–421.

Pihl E, Jurimae T. Relationship between body weight change and cardiovascular risk factors in male former athletes. Int J Obes Relat Metab Disord. 2001;25(7):1057–1062.

Baynes C, Henderson AD, Anyaoku V, Richmond W, Johnston DG, Elkeles RS. The influence of regional adiposity on atherogenic risk factors in men and women with type 2 diabetes. Diabet Med. 1991;8(5):458–463.

Al-Mukhtar SB, Al-Hamdani RY, Al-Naemi AH. Obesity and lipid profile in type 2 diabetics. Tikrit Med J. 2006;12(1):15–21.

Himabindu Y, Sriharibabu M, Alekhya K, Saisumanth K, Lakshmanrao N, Komali K. Correlations between anthropometry and lipid profile in type 2 diabetics. Indian J Endocr Metab.2013;17:727–9.

Glover SJ, Burgess PI, Harding SP, Hofland HW, Zijlstra EE, et al. Prevalence of diabetic retinopathy, cataract and visual impairment in patients with diabetes in sub-Saharan Africa. Br J Ophthalmol. 2012;96:156–161.

Chandni R, Ramamoorthy KP. Lipoprotein(a) in type 2 diabetic subjects and its relationship to diabetic microvascular complications. World J Diabetes. 2012;3(5):105–109.

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