Journal of Pharmaceutical and Biomedical Sciences

Primary Laparoscopic Common Bile Duct Exploration in Management of Choledocholithiasis in a Resource Constraint Setting: Our Experience

Saji Vargheese, Anis Akhtarkhavari, Satya Ranjan Patra, Shivakumar M Algud, Joash Jensen

Abstract


Introduction: Today’s options for biliary bypass procedures, in symptomatic choledocholithiasis, range from open surgery to laparo-endoscopic hybrid procedures. The aim of this study was to analyse the outcomes of patients with choledocholithiasis primarily treated with laparoscopic common bile duct exploration and Laparoscopic cholecystectomy (LCBDE + LC) in a remote setting with no facility of endoscopic retrograde cholangio- pancreatography and endoscopic sphincterotomy (ERCP + ES).

Methods: We performed a retrospective cross sectional study from March 2011 to June 2021. We included all symptomatic patients with common bile duct stones who underwent surgery by a single surgeon. A primary laparoscopic bile duct exploration with intraoperative cholangioscopy with T-tube placement with cholecystectomy was offered to all patients. Data was maintained in excel sheets and analysed with respect to their demographics, case records, operation notes and follow-up data. All significant intra operative and postoperative complications were recorded and our results were analysed. Results: A total of 5793 patients underwent laparoscopic cholecystectomy from march 2011 to June 2021 by a single surgeon. 58 patients were diagnosed to have choledocholithiasis and underwent LCBDE + LC for the same. We found a female predominance (62.1%), advanced mean age (48.3 years) and multiple comorbidities. Most patients had previous episodes of cholangitis. Mean operative time 218.74 min. Only one patient required conversion into an open procedure. CBD clearance rate was 96.5%. We had a median of 18 (12–60) months of follow-up. All patients except 2 had normalisation of liver enzymes during follow-up. Four patients required a second surgery. Port site infection, retained stones, retained T tube end and leak were encountered.

Conclusions: Laparoscopic CBD exploration with intraoperative cholangioscopy with cholecystectomy seems to be safe and effective treatment for patients with difficult common bile duct stones. This procedure can be a good first line option for patients with advanced age and multiple comorbidities, avoiding the cost and morbidities of ERCP + ES.


Keywords


Laparoscopic common bile duct exploration, choledocholithiasis, cholangitis, ERCP, T-tube.

Full Text:

References


European Association for the Study of the Liver (EASL). Electronic address: easloffice@easloffice.eu. EASL Clinical Practice Guidelines on the prevention, diagnosis and treatment of gallstones. J Hepatol. 2016 Jul;65(1):146-181. doi: 10.1016/j.jhep.2016.03.005.

Ahmed EA, Redwan AA. Impact of choledochotomy techniques during laparoscopic CBD exploration on short- and long-term clinical outcomes: Time to change concepts (a retrospective cohort study). Int J Surg. 2020 Nov;83:102-106. doi: 10.1016/j.ijsu.2020.08.043.

Pan L, Chen M, Ji L, Zheng L, Yan P, Fang J, Zhang B, Cai X. The Safety and Efficacy of Laparoscopic Common Bile Duct Exploration Combined with Cholecystectomy for the Management of Cholecysto-choledocholithiasis: An Up-to-date Meta-analysis. Ann Surg. 2018 Aug;268(2):247-253. doi: 10.1097/SLA.0000000000002731.

Cuendis-Velázquez A, E Trejo-Ávila M, Rosales-Castañeda E, Cárdenas-Lailson E, E Rojano-Rodríguez M, Romero-Loera S, A Sanjuan-Martínez C, Moreno-Portillo M. Laparoscopic Choledochoduodenostomy. Cir Esp. 2017 Aug-Sep;95(7):397-402. English, Spanish. doi: 10.1016/j.ciresp.2017.07.002.

Overby DW, Apelgren KN, Richardson W, Fanelli R; Society of American Gastrointestinal and Endoscopic Surgeons. SAGES guidelines for the clinical application of laparoscopic biliary tract surgery. Surg Endosc. 2010 Oct;24(10):2368-86. doi: 10.1007/s00464-010-1268-7.

Savita KS, Bhartia VK. Laparoscopic CBD Exploration. Indian J Surg. 2010 Oct;72(5):395-9. doi: 10.1007/s12262-010-0157-6.

Sanchez A, Rodriguez O, Bellorín O, Sánchez R, Benítez G. Laparoscopic common bile duct exploration in patients with gallstones and choledocholithiasis. JSLS. 2010 Apr-Jun;14(2):246-50. doi: 10.4293/108680810X12785289144395.

Shojaiefard A, Esmaeilzadeh M, Ghafouri A, Mehrabi A. Various techniques for the surgical treatment of common bile duct stones: a meta review. Gastroenterol Res Pract. 2009;2009:840208. doi: 10.1155/2009/840208.

Jiang C, Zhao X, Cheng S. T-Tube Use After Laparoscopic Common Bile Duct Exploration. JSLS. 2019 Jan-Mar;23(1):e2018.00077. doi: 10.4293/JSLS.2018.00077.

Isla IAM, Griniatsos J, Karvounis E, Arbuckle JD. Advantages of laparoscopic stented choledochorrhaphy over T-tube placement. Br J Surg. 2004 Jul;91(7):862-6. doi: 10.1002/bjs.4571.


Refbacks

  • There are currently no refbacks.


Copyright (c) 2022 Journal of Pharmaceutical and Biomedical Sciences

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.