Journal of Pharmaceutical and Biomedical Sciences

Brief Introduction to Depression

Kangyin Shi | Vol 08 | Issue 05 | Pp:22-26

Abstract


In present review article an attempt is made to introduce the cognitive function impairment in depression, including pathogenesis, clinical manifestation, influence factors and treatment. Series of articles about depression are reviewed, found several theories that account for possible pathogenesis of cognitive impairment in depression, such as Effort processing and cognitive speed hypotheses, Theory of inadequate function of hippocampal and Fronto-parietal network and default mode network. The article also highlighted the clinical manifestation of depression: executive dysfunction, memory disorders, disturbance of attention and response time delay. To explore the treatment of cognitive impairment, and to summarize factors and study consider age, severity of depression, life events, cause of disease, onset frequency and drug as main factors. On analysis of factors, treatment of cognitive impairment could be divided into two kinds: drug treatment, which includes antidepressants, and non-drug therapy, such as cognitive behavioral therapy, repetitive transcranial magnetic stimulation and psychotherapy.

Keywords


clinical manifestation, cognitive function impairment, depression, pathogenesis, treatment

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