Journal of Pharmaceutical and Biomedical Sciences

Metastatic Cervical Lymphadenopathy – Diagnosis by FNAC, A Tertiary Hospital Based Study

Amitkumar Bapuso Pandav, Kalpana Sulhyan, Pramila Patil

Abstract


Abstract:

Objective: Cervical lymphadenopathy is one of the commonest presentations in metastatic tumours . Fine needle aspiration cytology (FNAC) is simple, cost effective, and rapid method for diagnosis of metastatic cervical lymphadenopathy. FNAC not only give the diagnosis but also give the clue regarding the origin of primary tumor. Aim of this study is to study various metastatic tumours in cervical lymph nodes in known and occult primary tumors.

 

Methods: This study was carried study was out at Government Medical College and Hospital on 210 clinically diagnosed cases of cervical lymphadenopathy over a period of two years. FNAC was carried out in all these patients. Histopathological correlation was done in 40 cases. Patients included in the present study were in the age group of 11 months to 80 years.

 

Results: Tuberculous lymphadenopathy was the commonest (34%) followed by metastatic lymphadenopathy (24%) and reactive lymphadenitis (23%).The few cases were identified in the 'leukemic lymphadenopathy' category (1 %). Metastatic malignancy was most commonly seen in the fourth to fifth decade (28%). Squamous cell carcinoma was the most common metastatic lesion (74%), others are metastatic adenocarcinoma (12%), anaplastic carcinoma (6.%) Papillary carcinoma of thyroid (4%), Undifferentiated Malignant tumors (4%)

 

Conclusions: The most common metastatic tumors to cervical lymph node are Squamous cell carcinoma, Adenocarcinoma, Anaplastic carcinoma and papillary thyroid carcinoma. FNAC can aid in establishing the diagnosis in majority of cases. In certain situation it can be enough for diagnosis in proper clinical setting to avoid surgical procedure like biopsy. Diagnosis of metastatic cervical lymphadenopathy by FNAC is helpful in the initial management and also evaluating the response to therapy.


Keywords


Metastatic Cervical Lymphadenopathy, FNAC, Cervical Lymphadenopathy

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