Abstract
Objective To evaluate the anti-anemic activity of seeds of Trigonella foenum-graecum against phenyl hydrazine induced anemic rats.
Methods Rats were divided into 4 groups of 6 each. Group 1 was given normal saline and served as control and all other groups were given 40 mg/kg b. w of phenyl hydrazine for 2 days to induce anemia. Group 3 was treated with Dexorange syrup (200 mg/kg) and served as the standard. Group 4 was treated with seeds of Trigonella foenum-graecum (200 mg/kg). All the treatments were given orally. On completion of the experimental period, all the test substance/vehicle-treated rats were sacrificed and the plasma separated was used for estimating various biochemical as well as hematological parameters
as per standard procedures.
Results The experimental rats treated with seeds of Trigonella foenum-graecum at the dose level 200 mg/kg bw for 13 days revealed significant changes in biochemical and hematological parameters compared to phenyl hydrazine induced anemic rats.
Conclusion The present study concluded that the seeds of Trigonella foenum-graecum inhibits anemia induced by phenyl hydrazine in male albino rats.
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