Abstract
Streptococcus pyogenes (group A streptococcus) is one of the most common and ubiquitous human pathogen. It causes invasive and non-invasive human disease. The group A streptococcus infection can be further complicated by non-suppurative sequelae, such as rheumatic fever, which usually follows throat infection and glomerulonephritis. A total number of 215 children screened for ?-haemolytic streptococci from throat swabs and all culture positives are grouped by enzymatic extraction method
and ASO estimation was done. All results were analysed statistically. Out of the 215 throat swabs 22.5% positive for ?-haemolytic streptococci and grouped as group A 56.5% group C 31.1% group G 13.4%. All culture positives are sensitive to bacitracin 0.04 units and ASO estimated 54%. The proportion of antibiotic sensitivity was high for penicillin, vancomycin, cefotaxime and erythromycin, and the relative resistance to ampicillin and amoxicillin was seen. Our study suggests that the inappropriate use of antibiotic leads to drug resistance.
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