Journal of Pharmaceutical and Biomedical Sciences

Severe Skin Hypersensitivity Reaction to Local Infiltrating Anaesthetic Agent

Anjana Chaudhary, Sunita Chandrakar, Diwakar RK, Meena Naik

Abstract


Although the incidence of allergic reactions to local anaesthetics has decreased, they are still documented. Allergic reactions may consist of cutaneous lesions, urticaria, oedema or anaphylactic reactions. Severe hypersensitive reaction to local infiltration resulting in thin, charred and parchment-like skin with subsequent granuloma formation requiring debridement has not been reported earlier. We report a case of severe local skin reaction to lignocaine which is known to contain methylparaben as a preservative.

Keywords


hypersensitivity reaction, local anaesthetic agent, methylparaben

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References


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