Journal of Pharmaceutical and Biomedical Sciences

Login
Select Language
Subscription Login to verify subscription
Give a gift subscription
Article Tools
Print this article
Indexing metadata
How to cite item
Finding References
Review policy
Email this article (Login required)
Email the author(Login required)
Post a Comment (Login required)

An Uncommon Feature of Papillary Thyroid Carcinoma: A Case Report

Jayabal Pandiaraja, Devadhason Darwin Britto

Abstract


Most of the thyroid malignancies occur in either euthyroid or hypothyroid status. Thyroid malignancies with hyperthyroidism are very rare. There are numerous reasons for hyperthyroidism in thyroid cancer. The incidence of hyperthyroidism in thyroid malignancies were <1%. But recent report showed increased incidence due to mutation of thyroid receptors. The problem with hyperthyroidism and thyroid cancer was diagnostic difficulty and management part, because for most of the cases of hyperthyroidism thyroid malignancies are not suspected. This is a case report of papillary thyroid carcinoma presenting
in hyperthyroid patient who has diagnostic difficulty and management.

Keywords


papillary thyroid carcinoma, hyperthyroidism, total thyroidectomy

Full Text:

References


Gabriele R, Letizia C, Borghese M, De Toma G, Celi M, Izzo L, et al. Thyroid cancer in patients with hyperthyroidism. Horm Res. 2003;60(2):79–83.

Chao TC, Lin JD, Jeng LB, Chen MF. Thyroid cancer with concurrent hyperthyroidism. Arch Surg. 1999;134(2):130–4.

Ruggeri RM, Campennì A, Giovinazzo S, Saraceno G, Vicchio TM, Carlotta D, et al. Follicular variant of papillary thyroid carcinoma presenting as toxic nodule in an adolescent: coexistent polymorphism of the TSHR and Gs? genes. Thyroid. 2013; 23(2):239–42.

Sung TH, Man EM, Wong WW. Paediatric thyroid carcinoma in disguise: papillary thyroid carcinoma presenting with thyrotoxicosis and diffuse goiter. Pediatr Radiol. 2012;42(3):377–9.

Basaria S, Salvatori R. Thyrotoxicosis due to metastatic papillary thyroid cancer in a patient with Graves’ disease. J Endocrinol Invest. 2002;25(7):639–42.

Gulcelik MA, Gulcelik NE, Dinc S, Kuru B, Camlibel M, Alagol H. The incidence of hyperthyroidism in patients with thyroid cancer in an area of iodine deficiency. J Surg Oncol. 2006;94(1):35–9.

Gozu H, Avsar M, Bircan R, Claus M, Sahin S, Sezgin O, et al. Two novel mutations in the sixth transmembrane segment of the thyrotropin receptor gene causing hyperfunctioning thyroid nodules. Thyroid. 2005;15(4):389–97.

Ragni F, Pinelli D, Facchini M, Ghedi M, Piccini I, Pasini M, et al. [Thyroid carcinoma in hyperthyroid syndromes]. G Chir.1996;17(4):158–65.

dell’Erba L, Gerundini P, Caputo M, Bagnasco M. Association of hyperfunctioning thyroid adenoma with thyroid cancer presenting as “trapping only” nodule at 99mTcO4-scintigraphy. J Endocrinol Invest. 2003;26(11):1124–7.


Refbacks

  • There are currently no refbacks.


Copyright (c) 2015 Journal of Pharmaceutical and Biomedical Sciences

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.