Journal of Advances in Cardiology Research

Pharmacologic Reversal of Neuromuscular Blockade in Patients with Cardiac Disease: A New Age

Esperanza Martín-Mateos, Manuel Ángel Gómez-Ríos, Enrique Freire-Vila

Abstract


Postoperative residual curarization is one of the most clinically significant complications of the use of muscle relaxants.
Prevention of residual paralysis depends on judicious neuromuscular blockade management, monitoring, and use of reversal
agents. Administration of anticholinesterase agents is particularly problematic in patients with cardiac diseases. Thus, the use
of neostigmine should be individualized based on a risk/benefit analysis.Clinical data suggest that sugammadex is the drug of
choice for the reversal of neuromuscular blockade in the patient with cardiac disease.

Keywords


cardiac disease, general Anesthesia, neuromuscular blockade, residual paralysis, anticholinesterase agents, sugammadex

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